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Silica Based Chromatography Media

Silica Based Chromatography Media
Knowledge & Benefit Tech. developed the world leading technology to produce highly monodisperse, ultra-pure porous silica gel microspheres of any size ranging from 1.7 to 40 microns for high performance chromatography media. Meanwhile, Knowledge & Benefit Tech. developed the novel surface-bonding and end-capping technologies to provide non-polar packing media such as C18, C8 and C4.

Characterization
·Available in both reversed and normal phases
·Spherical particles with uniform size distribution
·Optimized pore struture
·High loading capacity
·High mechanical strength for multiple packing
Perfect end-capping

 

Fig. 1. SEM of uniform silica beads 

Column:

4.6 mm I.D. x 250 mm, KBsphere® Si-5 C18-120

Mobile phase:

Methanol/H2O=80/20

Flow Rate:

1 ml/min

Detection:

UV @ 254nm

Fig. 2. Separation reproducibility of C18-silica based media

Knowledge & Benefit Tech’s silica based chromatography media with optimized pore structure provides excellent selectivity, low back pressure, and exceptional batch-to-batch reproducibility. Knowledge & Benefit Tech. can offer the complete lines of silica based chromatography media including nomal phased and reversed phased chromatography media which are designed for laboratory and process scale purification of proteins, peptides, nucleic acids, antibiotics, and low molecular weight pharmaceuticals.

Table 4:List of silica based nomal phase chromatography media



Table 5:List of silica based reverse phase chromatography media



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